Pulling Down the Moon

Myo-inositol and D-chiro-inositol for PCOS

September 16, 2019

We’re sharing some of our best tips for managing PCOS with diet, lifestyle, and supplements to support patients not just during PCOS Awareness Month but all year long! We love working with clients with PCOS, because there is so much you can do by changing your habits to positively impact PCOS. A PCOS diagnosis is based on the Rotterdam criteria, which includes 1) irregular menstrual cycles with absent or irregular ovulation, 2) cysts on the ovaries, 3) elevated androgen levels. Two of these 3 characteristics must be present for a diagnosis of PCOS. 


Another common characteristic of women with PCOS is insulin resistance with 60-75% of women with PCOS have insulin resistance regardless of body weight. When you have insulin resistance, your insulin isn’t working as effectively as it should to get glucose out of your blood and into the cells of your body to be used for energy. The pancreas compensates by pumping out more insulin. These elevated insulin levels seem to be at the root of the elevated androgen/testosterone levels commonly found in women with PCOS. Thus addressing the insulin resistance in PCOS may help lower insulin and testosterone levels and improve menstrual cycle regularity. You can read more about managing insulin resistance here.


So this is where inositol comes in as a really helpful supplement. Inositol is a nutrient found in beans, grains, fruit, and nuts that research has shown to be beneficial for PCOS. There are 9 different forms of inositol, but two forms have been shown to be beneficial for PCOS. These are myo-inositol and D-chiro-inositol. Myo-inositol in combination with D-chiro-inositol may help lower insulin and testosterone levels and increase menstrual cycle regularity in women with PCOS making it a very helpful tool in your PCOS management strategy. The body’s normal ratio of myo-inositol to D-chiro-inositol is 40:1, and a recent study has shown that this is the most effective ratio in supplemental form for restoring ovulation in PCOS. At Pulling Down the Moon, we carry Ovasitol, which contains the recommended 40:1 ratio of myo-inositol to D-chiro-inositol.


Beyond PCOS, myo-inositol also may improve egg quality and may reduce risk for gestational diabetes when taken during pregnancy. Book a nutrition appointment to further discuss ways to help manage your PCOS and try a complimentary Community Yoga for Fertility class!


Reference: Nordio M, Basciani S, Camajani E. The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS: comparison to other ratios. Eur Rev Med Pharm Sci. 2019;23:5512-5521.

Share on Social

Discuss With Us

Our Latest Resources

February 18, 2025
Spring arrives next month, and with it, more cold days (perhaps even snow)! But March also brings the promise of new life. We love this time of year. The ground starts to smell fresh and ripe. Small green buds begin to swell from the earth reaching up, up, up. Birds chatter in the trees. The sun stays in the sky a little longer each day. After a long, cold winter of hibernation, spring restores nature’s beauty. Spring inspires us to restore ourselves, too and these self-care techniques will lead you to restoration of mind, body and spirit. Hydrate. Drink a glass or two of water first thing in the morning. Keeping yourself hydrated helps boost your mood, improves brain power and protects you against disease. Make a gratitude list. Spending just a few minutes a day writing down what you are grateful for can dramatically shift your day. The more gratitude you have, the more open to abundance you become. Breathe. Set aside a few minutes each day to practice breathing. There are so many benefits! Among them, diaphragmatic breathing alleviates stress, reduces pain, strengthens internal muscles and moves blood to organs and tissues. If you’re not sure how to get started, try our Breathe & Restore Workshop or schedule an Soothe the Senses: Calm the Nervous System Fertility Enhancing Massage™ to receive some hands-on breath work coaching. Stretch. Five to 10 minutes of stretching in the morning increases energy levels, enhances circulation, reduces injury and centers your mind. Even better is a regular yoga practice. Get started by downloading the Fully Fertile App today to give you a jump start! Our next Signature Yoga for Fertility Series begins on Monday, February 24th to reduce anxiety and stress by 20% or more in just six weeks. Eliminate something from your diet that isn’t serving you. I nstead of overhauling your entire diet, start by taking out one food that doesn’t nourish your body. Replace it with a different item that supports your desire for restoration. Learn even more by working with scheduling a nutrition consult ! We look forward to seeing you virtually or in-person at one of our centers to help you get started. Many wishes for a beautiful spring!
A man is comforting a woman who is sitting on a couch.
January 27, 2025
Connect with others who understand your journey. Discover online infertility support groups to share experiences, gain advice, and find emotional sup
January 21, 2025
Discover Our New Testing Options to Support Your Fertility Journey
More Posts
Share by: