Pulling Down the Moon

CoQ10 Improves Egg and Embryo Quality

August 2, 2016

An exciting new study shows promising results for CoQ10 supplementation in women with poor ovarian reserve doing IVF. In the study, 186 women under age 35 with poor ovarian reserve, defined as Anti-Müllerian hormone (AMH) < 1.2 ng/mL, and antral follicle count (AFC) < 5, were randomized to receive either treatment with 600 mg CoQ10 (200 mg 3 times per day) or control (no treatment) for 60 days leading up to their IVF cycle.

The results were pretty striking. The CoQ10 group had significantly more high quality day 3 embryos (1 vs. 0 in the control group), significantly less gonadotropins needed for stimulation, significantly more eggs retrieved (4 vs. 2 in the control group), and significantly higher fertilization rate (67% vs. 45% in the control group). In addition, significantly more patients who took CoQ10 had embryos to freeze (18.4% vs. 4.3% in the control group). The CoQ10 group also had higher pregnancy rates (32% vs. 17% in the control group) and higher live birth rates (29% vs. 16% in the control group), but these results were not statistically significant.



CoQ10 is an antioxidant and plays an essential in energy production in our body cells, including maturing eggs. CoQ10 is thought to exert its beneficial effects by neutralizing free radicals that could damage the DNA or other structures within the egg. Damage to DNA can prevent fertilization or result in a nonviable embryo. In addition, because of CoQ10’s role in energy production, CoQ10 likely also supports the energy needs of maturing eggs, thus leading to better quality eggs and embryos. CoQ10 tends to be a safe and well-tolerated supplement, and in this study, there were no adverse effects reports from supplementing with CoQ10.

Absorption of CoQ10 is best when the dose is divided into 3 doses with meals during the day. Because CoQ10 is fat-soluble, having fat with CoQ10 increases the absorption.


Reference: Xu Y, Nisenblat V, Cuiling L, et al. Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial. Reproductive Biology and Endocrinology. 2018;16:29.


**Save 25% off CoQ10 in June with the promo code EGG25! Available in-center and online while supplies last.

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February 18, 2025
Spring arrives next month, and with it, more cold days (perhaps even snow)! But March also brings the promise of new life. We love this time of year. The ground starts to smell fresh and ripe. Small green buds begin to swell from the earth reaching up, up, up. Birds chatter in the trees. The sun stays in the sky a little longer each day. After a long, cold winter of hibernation, spring restores nature’s beauty. Spring inspires us to restore ourselves, too and these self-care techniques will lead you to restoration of mind, body and spirit. Hydrate. Drink a glass or two of water first thing in the morning. Keeping yourself hydrated helps boost your mood, improves brain power and protects you against disease. Make a gratitude list. Spending just a few minutes a day writing down what you are grateful for can dramatically shift your day. The more gratitude you have, the more open to abundance you become. Breathe. Set aside a few minutes each day to practice breathing. There are so many benefits! Among them, diaphragmatic breathing alleviates stress, reduces pain, strengthens internal muscles and moves blood to organs and tissues. If you’re not sure how to get started, try our Breathe & Restore Workshop or schedule an Soothe the Senses: Calm the Nervous System Fertility Enhancing Massage™ to receive some hands-on breath work coaching. Stretch. Five to 10 minutes of stretching in the morning increases energy levels, enhances circulation, reduces injury and centers your mind. Even better is a regular yoga practice. Get started by downloading the Fully Fertile App today to give you a jump start! Our next Signature Yoga for Fertility Series begins on Monday, February 24th to reduce anxiety and stress by 20% or more in just six weeks. Eliminate something from your diet that isn’t serving you. I nstead of overhauling your entire diet, start by taking out one food that doesn’t nourish your body. Replace it with a different item that supports your desire for restoration. Learn even more by working with scheduling a nutrition consult ! We look forward to seeing you virtually or in-person at one of our centers to help you get started. Many wishes for a beautiful spring!
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